Eat to Live
A meager diet may give you health and long life, hut it&39;s not much fun--and it might not e-yen be necessary. We may be aB.le to hang on to most of that youthful vigor even if we don&39;t start todiet until old age.
Stephen Spindler and his colleagues from the University of Californiaat Riverside have found that some of an elderly mouse&39;s liver genes can be made to behave as they did when the mouse wasyoung simply by limiting its food for four weeks. The geneticrejuvenation won&39;t reverse other dam- age causedby time for the mouse, B.ut could help its liver metabolize drugs or get rid of toxins.
Spindler&39;s team fed three mice anormal diet for their whole lives, and fed another three onhalf-rations. Three more mice were switched from the normal diet to half-feed for amonth whenthey were 34 months old--equivalent to about 70 human years.
The researchers checked the activity of 11,000 genes from the mouse livers, and found that46 changed with age in the normally fed mice. The changes were associated with things like in-flammation and free radical production--probably bad news for mouse health. In the mice that haddieted all their lives, 27 of those 46 genes continued to behave like young genes. but the most sur-prising finding was that the mice that only started dieting in old age alsobenefited from 70 percentof these gene changes.
"This is the first indication that these effects kick in pretty quickly," says HuB.er Warnerfrom the National Institute on Aging near Washington D. C.
No one yet knows if calorie restriction works in people as it does in mice, B.ut Spindler ishopeful. "There&39;s attracting and tempting evidence out there that it will work," he says.
If it does work in people, there might be good reasons for rejuvenating the liver. As we get ol-der, our bodies are less efficient at metabolizing drugs, for example. A.brief period of time of die-ting, says Spindler, could be enough to make sure adrug is effective.
but Spindler isn&39;t sure the trade-off is worth it. "The mice get less disease,they live longer,but they&39;re hungry," he says. "Even seeing what adiet does, it&39;s still hard to go to arestaurantand say: &39; I can only eat half of that. &39;"
Spindler hopes we soon won&39;t need to diet at all. His company, Lifespan Genetics in Califor-nia, is looking for drugs that have the effects of calorie restriction.
According to the passage, which of the following is NOT true? 查看材料
A.Eating less than usual might make us live longer
B.If we go on adiet when old, we may keep healthy
C.Dieting might not be needed
D.We have to begin dieting since childhood
I stared at the paper,21 reading, couldn’ t help thinking.
Crocodiles are lazy animals as a rule,but they can move like lightening when they want to. And they don’ t mind hurrying 22 they’ re hungry. There used to be lots in Indian rivers, living on fish mostly;but what’ s a little fish for a fifteen-foot crocodile? They ate people,fisherman or anyone else delicious enough to get too near;women doing the 23,or children playing at the water’ s24 A hungry crocodile’ s mouth 25 over a meal with a sound like a gunshot. A big fellow can 26 in a man in two bites (咬).
That woman’ s husband crossed rivers 27 from one crocodile’ s back to the next. I believe it. It had to be done quickly before the creature could see what was happening. It wasn’ t 28 a brave, active man;and no doubt he improved with practice. He could never look 29 while crossing.
The wife used to watch him—I felt sure of that. She lived 30 the adventure, the 31 excitement of it all. Their real life was with tigers,snakes".It’s no wonder she wrote 32 poetry.
Then he died.I imagined how she felt. Was there another man 33 him in India, in the world? She was still young,hardly a sitting-room widow(寡妇)“I must 34 ,too. she said to herself. So she did what she felt she had to do. A 35 probably,to her head.
But her young son,their son? Was her love for him nothing compared to her husband? Well,what do you think?
A.started
B.began
C.finished
D.stopped
A.whenever
B.for
C.because
D.as
A.shopping
B.washing
C.cooking
D.cleaning
A.border
B.end
C.side
D.edge
A.looks
B.sends
C.shuts
D.turns
A.go
B.take
C.eat
D.catch
A.jumping
B.runni
C.walking
D.marching
A.over
B.for
C.behind
D.beyond
A.up
B.down
C.back
D.right
A.without
B.till
C.for
D.on
A.lively
B.friendly
C.deathly
D.lovely
A.angry
B.exciting
C.sad
D.interesting
A.like
B.as
C.with
D.before
A.go
B.practice
C.jump
D.shoot
A.pen
B.gun
C.comb
D.stone
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